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CBIC Certified Infection Control Exam Sample Questions (Q94-Q99):

NEW QUESTION # 94
An HBsAb-negative employee has a percutaneous exposure to blood from a Hepatitis B surface antigen (HBsAg) positive patient. Which of the following regimens is recommended for this employee?

A. Immune serum globulin and hepatitis B vaccine
B. Hepatitis B immune globulin (HBIG) alone
C. Hepatitis B vaccine alone
D. Hepatitis B immune globulin (HBIG) and hepatitis B vaccine

Answer: D

Explanation:
The correct answer is D, "Hepatitis B immune globulin (HBIG) and hepatitis B vaccine," as this is the recommended regimen for an HBsAb-negative employee with a percutaneous exposure to blood from an HBsAg-positive patient. According to the Certification Board of Infection Control and Epidemiology (CBIC) guidelines, which align with recommendations from the Centers for Disease Control and Prevention (CDC) and the Advisory Committee on Immunization Practices (ACIP), post-exposure prophylaxis (PEP) for hepatitis B virus (HBV) exposure depends on the employee's vaccination status and the source's HBsAg status. For an unvaccinated or known HBsAb-negative individual (indicating no immunity) exposed to HBsAg-positive blood, the standard PEP includes both HBIG and the hepatitis B vaccine. HBIG provides immediate passive immunity by delivering pre-formed antibodies, while the vaccine initiates active immunity to prevent future infections (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency 3.2 - Implement measures to prevent transmission of infectious agents). The HBIG should be administered within 24 hours of exposure (preferably within 7 days), and the first dose of the vaccine should be given concurrently, followed by the complete vaccine series.
Option A (immune serum globulin and hepatitis B vaccine) is incorrect because immune serum globulin (ISG) is a general immunoglobulin preparation and not specific for HBV; HBIG, which contains high titers of anti-HBs, is the appropriate specific immunoglobulin for HBV exposure. Option B (hepatitis B immune globulin [HBIG] alone) is insufficient, as it provides only temporary passive immunity without initiating long- term active immunity through vaccination, which is critical for an unvaccinated individual. Option C (hepatitis B vaccine alone) is inadequate for immediate post-exposure protection, as it takes weeks to develop immunity, leaving the employee vulnerable in the interim.
The recommendation for HBIG and hepatitis B vaccine aligns with CBIC's emphasis on evidence-based post- exposure management to prevent HBV transmission in healthcare settings (CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competency 3.1 - Collaborate with organizational leaders).
This dual approach is supported by CDC guidelines, which prioritize rapid intervention to reduce the risk of seroconversion following percutaneous exposure (CDC Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HBV, HCV, and HIV, 2013).
References: CBIC Practice Analysis, 2022, Domain III: Infection Prevention and Control, Competencies 3.1 - Collaborate with organizational leaders, 3.2 - Implement measures to prevent transmission of infectious agents. CDC Updated U.S. Public Health Service Guidelines for the Management of Occupational Exposures to HBV, HCV, and HIV, 2013.

NEW QUESTION # 95
An infection preventionist has been asked to participate in a process improvement team to standardize disinfection and sterilization practices. Team activities should include all of the following EXCEPT:

A. Observing disinfection and sterilization practices.
B. Conducting outcome measurement after all changes are implemented.
C. Asking central supply and operating room managers to join the team.
D. Performing a literature review on central supply and sterilization.

Answer: B

Explanation:
The CBIC Certified Infection Control Exam Study Guide (6th edition) emphasizes that effective process improvement relies on a structured, data-driven approach that includes baseline assessment, intervention, and ongoing evaluation. A key principle of quality improvement is that outcomes must be measured before and after changes are implemented in order to determine whether an intervention resulted in improvement.
Option D is the correct "EXCEPT" choice because limiting outcome measurement to only after changes are implemented prevents meaningful comparison and makes it impossible to determine effectiveness. Without baseline data, improvements cannot be quantified, trends cannot be assessed, and unintended consequences may go unrecognized. The Study Guide stresses that baseline measurements are essential to evaluate process performance and to support evidence-based decision-making.
Options A, B, and C are all appropriate and expected activities. Direct observation helps identify workflow gaps and variation in practice. Inclusion of central supply and operating room leadership ensures multidisciplinary engagement and operational insight. Conducting a literature review supports alignment with current evidence, standards, and best practices for disinfection and sterilization.
For the CIC exam, it is important to recognize that continuous measurement throughout the improvement cycle-not only after implementation-is required for successful standardization and sustainability of infection prevention practices.

NEW QUESTION # 96
There are four cases of ventilator-associated pneumonia in a surgical intensive care unit with a total of 200 ventilator days and a census of 12 patients. Which of the following BEST expresses how this should be reported?

A. More information is needed regarding ventilator days per patient
B. Postoperative pneumonia rate of 6% in SICU patients
C. 20 ventilator-associated pneumonia cases/1000 ventilator days
D. Ventilator-associated pneumonia rate of 2%

Answer: C

Explanation:
The standard way to report ventilator-associated pneumonia (VAP) rates is:

Why the Other Options Are Incorrect?
* A. Ventilator-associated pneumonia rate of 2% - This does not use the correct denominator (ventilator days).
* C. Postoperative pneumonia rate of 6% in SICU patients - Not relevant, as the data focuses on VAP, not postoperative pneumonia.
* D. More information is needed regarding ventilator days per patient - The total ventilator days are already provided, so no additional data is required.
CBIC Infection Control Reference
APIC and NHSN recommend reporting VAP rates as cases per 1,000 ventilator days.

NEW QUESTION # 97
Catheter associated urinary tract infection (CAUTI) improvement team is working to decrease CAUTIs in the hospital. Which of the following would be a process measure that would help to reduce CAUTI?

A. Rate of bloodstream infections secondary to CAUTI
B. Staff compliance to proper insertion technique
C. CAUTI rate per 1000 catheter days
D. Standardized Infection Ratio per unit

Answer: B

Explanation:
Aprocess measureassesses how well healthcare personnel follow specific procedures known to prevent infection. In the case of CAUTI (Catheter-Associated Urinary Tract Infection), monitoringstaff compliance with proper insertion techniqueis a direct process measure.
* According to theAPIC/JCR Workbook, effective CAUTI prevention involves evaluating compliance with proper catheter insertion and maintenance practices. Monitoring this behavior is a process measure that directly affects outcomes like infection rate reduction.
* TheCBIC Study Guidealso emphasizes usingcompliance with evidence-based insertion techniques as a strategy to measure and improve CAUTI prevention efforts.
* APIC Textnotes that "a process measure focuses on a process or the steps in a process that leads to a specific outcome." This includes monitoring healthcare staff performance related to proper catheter insertion and care.
* Incorrect answer rationale:
* A. CAUTI rate per 1000 catheter days- This is anoutcome measure, not a process measure.
* B. Standardized Infection Ratio per unit- Also anoutcome/benchmarking metric.
* C. Rate of bloodstream infections secondary to CAUTI- This is anoutcome, not a process.
References:
APIC/JCR Infection Prevention and Control Workbook, 4th Edition, Chapter 12 - CAUTI Assessment APIC Text, 4th Edition, Chapter 17 - Performance Measures CBIC Study Guide, 6th Edition, Core Competency: Surveillance and Epidemiologic Investigation

NEW QUESTION # 98
A patient with a history of Clostridioides difficile is admitted to the hospital. The patient is asymptomatic for diarrheal symptoms; however, the provider prescribes an antibiotic. What type of antimicrobial therapy is applied in this scenario?

A. Inappropriate
B. Empiric
C. Prophylactic
D. Targeted

Answer: C

Explanation:
The CBIC Certified Infection Control Exam Study Guide (6th edition) defines prophylactic antimicrobial therapy as the use of antibiotics to prevent infection in the absence of clinical signs or symptoms of active disease. In this scenario, the patient has a history of Clostridioides difficile infection but is currently asymptomatic for diarrhea or other CDI manifestations. The antibiotic is therefore not being used to treat active infection.
Empiric therapy (Option A) is initiated when infection is suspected but the causative organism has not yet been identified-this does not apply here, as the patient has no symptoms suggesting infection. Targeted therapy (Option D) requires laboratory confirmation of a specific pathogen, which is also not present. While prescribing antibiotics in patients with prior CDI may be clinically questionable depending on indication and stewardship principles, the type of therapy being applied is best categorized as prophylactic, not inappropriate, based on standard antimicrobial definitions.
The Study Guide emphasizes that antimicrobial stewardship programs carefully evaluate prophylactic antibiotic use because unnecessary exposure can disrupt normal flora and increase the risk of CDI recurrence.
However, from a classification standpoint, antibiotics given without signs of active infection fall under prophylactic use.
For CIC exam preparation, it is important to correctly identify antimicrobial intent, even when clinical appropriateness may be debatable.

NEW QUESTION # 99
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